| Date | Location | Result | |
| 03/04/22 | Kansas City, MO | Neb.-Kearney 52, Northwest Mo. St. 47 | Box score |
| 02/26/22 | Maryville, MO | Fort Hays St. 69, Northwest Mo. St. 47 | Box score |
| 02/23/22 | Kearney, NE | Neb.-Kearney 68, Northwest Mo. St. 51 | Box score |
| 02/21/22 | Maryville, MO | Northwest Mo. St. 77, Emporia St. 65 | Box score |
| 02/19/22 | Maryville, MO | Northwest Mo. St. 58, Washburn 53 (OT) | Box score |
| 02/12/22 | Joplin, MO | Mo. Southern St. 56, Northwest Mo. St. 49 | Box score |
| 02/10/22 | Pittsburg, Kan. -- John Lance Arena | Pittsburg St. 66, Northwest Mo. St. 62 | Box score |
| 02/08/22 | Emporia, KS | Northwest Mo. St. 70, Emporia St. 54 | Box score |
| 02/05/22 | St. Joseph, MO | Missouri Western 68, Northwest Mo. St. 52 | Box score |
| 01/29/22 | Maryville, MO | Central Mo. 58, Northwest Mo. St. 54 | Box score |
| 01/27/22 | Maryville, MO | Northwest Mo. St. 63, Lincoln (MO) 46 | Box score |
| 01/22/22 | Wichita, KS | Northwest Mo. St. 54, Newman 42 | Box score |
| 01/20/22 | Edmond, OK | Northwest Mo. St. 79, Central Okla. 69 | Box score |
| 01/17/22 | Topeka, KS | Washburn 58, Northwest Mo. St. 52 | Box score |
| 01/15/22 | Maryville, MO | Neb.-Kearney 67, Northwest Mo. St. 60 | Box score |
| 01/12/22 | Hays, KS | Fort Hays St. 63, Northwest Mo. St. 60 | Box score |
| 01/03/22 | Maryville, MO | Northwest Mo. St. 66, Pittsburg St. 62 | Box score |
| 01/01/22 | Maryville, MO | Northwest Mo. St. 61, Mo. Southern St. 51 | Box score |
| 12/18/21 | Maryville, MO | Northwest Mo. St. 49, Missouri Western 46 | Box score |
| 12/15/21 | Maryville, MO | Northwest Mo. St. 54, McKendree 29 | Box score |
| 12/13/21 | Warrensburg, MO | Central Mo. 60, Northwest Mo. St. 57 | Box score |
| 12/11/21 | Jefferson City, MO | Northwest Mo. St. 56, Lincoln (MO) 43 | Box score |
| 12/04/21 | Maryville, MO | Northwest Mo. St. 67, Rogers St. 59 | Box score |
| 12/02/21 | Maryville, MO | Northwest Mo. St. 75, Northeastern St. 55 | Box score |
| 11/27/21 | Northwest Mo. St. 65, Winona St. 62 | Box score | |
| 11/26/21 | Topeka, KS | Northwest Mo. St. 73, Rockhurst 63 | Box score |
| 11/22/21 | Maryville, MO | Northwest Mo. St. 68, Missouri S&T 48 | Box score |
| 11/13/21 | Maryville, MO | Northwest Mo. St. 53, Minn.-Crookston 48 | Box score |
| 11/12/21 | Maryville, MO | Southwest Minn. St. 64, Northwest Mo. St. 48 | Box score |