| Date | Location | Result | |
| 03/26/22 | Evansville, IN | Northwest Mo. St. 67, Augusta 58 | Box score |
| 03/24/22 | Evansville, IN | Northwest Mo. St. 70, Black Hills St. 57 | Box score |
| 03/22/22 | Evansville, IN | Northwest Mo. St. 61, Bentley 43 | Box score |
| 03/15/22 | Sioux Falls, SD | Northwest Mo. St. 70, Augustana (SD) 56 | Box score |
| 03/13/22 | Sioux Falls, SD | Northwest Mo. St. 70, Washburn 55 | Box score |
| 03/12/22 | Sioux Falls, SD | Northwest Mo. St. 69, MSU Moorhead 54 | Box score |
| 03/06/22 | Kansas City, MO | Northwest Mo. St. 84, Washburn 76 | Box score |
| 03/05/22 | Kansas City, MO | Northwest Mo. St. 53, Fort Hays St. 50 | Box score |
| 03/03/22 | Kansas City, MO | Northwest Mo. St. 72, Rogers St. 50 | Box score |
| 02/26/22 | Maryville, MO | Northwest Mo. St. 57, Fort Hays St. 49 | Box score |
| 02/23/22 | Kearney, NE | Northwest Mo. St. 77, Neb.-Kearney 67 | Box score |
| 02/21/22 | Maryville, MO | Emporia St. 76, Northwest Mo. St. 75 | Box score |
| 02/19/22 | Maryville, MO | Washburn 60, Northwest Mo. St. 59 | Box score |
| 02/12/22 | Joplin, MO | Northwest Mo. St. 71, Mo. Southern St. 64 | Box score |
| 02/10/22 | Pittsburg, Kan. -- John Lance Arena | Northwest Mo. St. 80, Pittsburg St. 68 | Box score |
| 02/08/22 | Emporia, KS | Emporia St. 75, Northwest Mo. St. 56 | Box score |
| 02/05/22 | St. Joseph, MO | Northwest Mo. St. 84, Missouri Western 61 | Box score |
| 02/01/22 | Maryville, MO | Northwest Mo. St. 82, Mo. Southern St. 71 | Box score |
| 01/29/22 | Maryville, MO | Northwest Mo. St. 89, Central Mo. 49 | Box score |
| 01/27/22 | Maryville, MO | Northwest Mo. St. 96, Lincoln (MO) 63 | Box score |
| 01/22/22 | Wichita, KS | Northwest Mo. St. 82, Newman 53 | Box score |
| 01/20/22 | Edmond, OK | Central Okla. 76, Northwest Mo. St. 75 (OT) | Box score |
| 01/17/22 | Topeka, KS | Northwest Mo. St. 71, Washburn 63 | Box score |
| 01/15/22 | Maryville, MO | Northwest Mo. St. 80, Neb.-Kearney 65 | Box score |
| 01/12/22 | Hays, KS | Northwest Mo. St. 74, Fort Hays St. 60 | Box score |
| 01/03/22 | Maryville, MO | Northwest Mo. St. 74, Pittsburg St. 64 | Box score |
| 12/29/21 | Maryville, MO | Northwest Mo. St. 85, St. Mary (KS) 59 | Box score |
| 12/18/21 | Maryville, MO | Northwest Mo. St. 101, Missouri Western 63 | Box score |
| 12/13/21 | Warrensburg, MO | Northwest Mo. St. 77, Central Mo. 53 | Box score |
| 12/11/21 | Jefferson City, MO | Northwest Mo. St. 84, Lincoln (MO) 54 | Box score |
| 12/04/21 | Maryville, MO | Northwest Mo. St. 90, Rogers St. 57 | Box score |
| 12/02/21 | Maryville, MO | Northwest Mo. St. 86, Northeastern St. 74 | Box score |
| 11/26/21 | Maryville, MO | Northwest Mo. St. 98, Briar Cliff (IA) 66 | Box score |
| 11/23/21 | Maryville, MO | Northwest Mo. St. 86, Truman 76 | Box score |
| 11/19/21 | St. Joseph, MO | Northwest Mo. St. 78, Mo.-St. Louis 65 | Box score |
| 11/14/21 | Kansas City, Mo. -- Municipal Auditorium | Northwest Mo. St. 75, Ark.-Monticello 52 | Box score |
| 11/13/21 | Kansas City, Mo. -- Municipal Auditorium | Sioux Falls 83, Northwest Mo. St. 77 | Box score |
| 11/07/21 | St. Joseph, MO | Northwest Mo. St. 64, Seattle Pacific 59 | Box score |
| 11/06/21 | St. Joseph, MO | Northwest Mo. St. 68, Northern St. 55 | Box score |